Research

Major Research Interests

Single-molecule nanomechanics: we employ single-molecule atomic force microscopy and optical tweezer approaches to acquire quantitative measurements of protein conformation and protein-protein interactions. 

Our research focuses on three aspects:

  1. Interfaces between biopolymers and circulatory flow
  2. Cellular mechanosensing and mechanotransduction
    • Platelet mechanosensing and activation
    • Endothelial mechanosensing and mechanotransduction
  3. Mechanobiology of intercellular interactions
    • Lymphocyte adhesion mediated by integrins
    • Virushost cell interaction