Project Name

Deformations and Rupture of Lipid Vesicles in Fluid Flow

Deformations and Rupture of Lipid Vesicles in Fluid Flow

Another project that we are working on now is to understand the deformations and rupture of lipid vesicles in fluid flow. The pore formation and rupture of lipid vesicles cannot be captured by continuum scale models. Thus, we are working on coupling the coarse-grained...

Multiscale Modeling of Biological Membrane

Multiscale Modeling of Biological Membrane

Quantifying the characteristics of biological membranes is challenging. The multiscale nature of biological phenomena, complex structure, and non-equilibrium properties are some of the main difficulties. The focus of this project...

Drug Delivery via Red Blood Cell Hitchhikers

Drug Delivery via Red Blood Cell Hitchhikers

Among all drug carriers, erythrocytes (known as red blood cells [RBC]) represent a potentially fascinating and, in some respects, unique carrier for drug delivery. Delivery of nanoparticle (NP)-based agents via their attachment...

Intracellular Drug Delivery via Rapid Squeezing

Intracellular delivery of functional macromolecules is essential for biological research and medical application. For example, DNA and RNA delivery has been studied for gene therapy and CRISPR-based biosensing; enzymes and other...

Study of Shear Induced Red Blood Cell Damage

Study of Shear Induced Red Blood Cell Damage

Cell damage often arises when cells are transported inflow by various medical devices such as a syringe pump, artificial heart, heart valve, and bio-printer. The damage may be caused by direct contact with artificial surfaces or high shear stresses in these devices....

Microcirculation

Microcirculation

I am also working on this project. The experiments are doing by Anthony. Actually, we plan to fabricate a vessel network. Afterward, we want to perfuse the blood flow in it. I am sure that Anthony knows better than me.  On the numerical side, we plan to integrate the...

Hemodynamics of Circulating Tumor Clusters

Hemodynamics of Circulating Tumor Clusters

It was estimated that 8 million people die from cancer over the world in each year, and more than 90% of the patients were killed by the metastasis development. In the development of carcinomas, which account for 80 to 90 percent...