Google Scholar: https://scholar.google.com/citations?user=FuSh8cwAAAAJ&hl=es

 Research Gate: https://www.researchgate.net/profile/Tomas-Gonzalez-Fernandez-2

2024

CRISPR-GEM: A Novel Machine Learning Model for CRISPR Genetic Target Discovery and Evaluation. J. P. Graham, Y. Zhang, L. He, T. Gonzalez-Fernandez. ACS Synthetic Biology (2024).

Neutrophil Granulopoiesis Optimized through Ex Vivo Expansion of Hematopoietic Progenitors in Engineered 3D Gelatin Methacrylate Hydrogels. E. Cirves, A. Vargas, J. K. Leach, S. I. Simon., T. Gonzalez-Fernandez Adv. Healthc. Mater. (2024).

Immunomodulatory Strategies for Cartilage Regeneration in Osteoarthritis. O. Kennedy, A. Kitson, C. Okpara, L. W. Chow, T. Gonzalez-Fernandez. Tissue Engineering Part A (2024).

Solvent‐Cast 3D Printing with Molecular Weight Polymer Blends to Decouple Effects of Scaffold Architecture and Mechanical Properties on Mesenchymal Stromal Cell Fate. J. W. Tolbert, T. French, A. Kitson, C. Okpara, D. E. Hammerstone, S. Lazarte, T. F. Babuska, T. Gonzalez‐Fernandez, B. A. Krick, L. W. Chow. Journal of Biomedical Materials Research Part A (2024).

2023

CRISPR Strategies for Stem Cell Engineering: A New Frontier in Musculoskeletal Regeneration. J.P.Graham,  L. Werba,  I. Federico, T. Gonzalez-Fernandez. European Cells and Materials 46 (2023) 91-118.

A Bioactive Material with Dual Integrin-targeting Ligands Regulates Specific Endogenous Cell Adhesion and Promotes Vascularized Bone Regeneration in Adult and Fetal Bone Defects. D. Hao, R. Liu, T. Gonzalez-Fernandez, C. Pivetti, J. E. Jackson, E. S. Kulubya, H. Jiang, H. Ju, W. Liu, A.Panitch, K. S. Lam, J. K. Leach, D. L. Farmer, A. Wang. Bioactive Materials (2023).

2022

Engineered Cell‐Secreted Extracellular Matrix Modulates Cell Spheroid Mechanosensing and Amplifies Their Response to Inductive Cues for the Formation of Mineralized Tissues. T. Gonzalez‐Fernandez, A. J. Tenorio, A. M. Saiz Jr, J. K. Leach. Advanced Healthcare Materials (2022) 2102337.

Journal back cover:

2021

Alginate-based Bioinks for 3D Bioprinting and Fabrication of Anatomically Accurate Bone Grafts. T. Gonzalez-Fernandez, A. J. Tenorio, K. T. Campbell, E. A. Silva, J. K. Leach. Tissue Engineering Part A (2021) 27 (17-18), 1168-1181.

2020

Tunable Fibrin-Alginate Interpenetrating Network Hydrogels to Support Cell Spreading and Network Formation. E. Vorwald, T. Gonzalez-Fernandez, S. Joshee, P. Sikorski, J. K. Leach. Acta Biomaterialia, 108 (2020) 142-152.

Three-Dimensional Printed Stamps for the Fabrication of Patterned Microwells and High-Throughput Production of Homogeneous Cell Spheroid. Gonzalez-Fernandez, A. J. Tenorio, J.K. Leach. 3D Printing and Additive Manufacturing (2020).

Osteogenic Preconditioning in Perfusion Bioreactors Improves Vascularization and Bone Formation by Human Bone Marrow Aspirates. N. Harvestine, T. Gonzalez-Fernandez, A. Sebastian, N. R. Hum, D.C. Genetos, G. G. Loots, J. K. Leach. Science Advances, 6 (2020) eaay2387.

Multi-peptide Presentation and Hydrogel Mechanics Jointly Enhance Therapeutic Duo-potential of Entrapped Stromal Cells. P. Hung*, T. Gonzalez-Fernandez*, J. B. Lin, T. Campbell, Y. B. Lee, A. Panitch, E. Alsberg, J. K. Leach. Biomaterials, 245 (2020) 119973. (*Authors contributed equally).

2019

Engineering Immunomodulating Scaffolds by Modulating Particle Size. R. Mahon, D. C. Browe, T. Gonzalez-Fernandez, P. Pitacco, I. T. Whelan, C. Hobbs, V. Nicolosi, K. Cunningham, K. H. Mills, D. J. Kelly, A. Dunne. Biomaterials, 239 (2019) 119833.

Bio-instructive Materials for Musculoskeletal Regeneration. Gonzalez-Fernandez, P. Sikorski, J.K. Leach. Acta Biomaterialia, 96 (2019) 20-34.

Hypoxia Mimicking Hydrogels to Regulate the Fate of Transplanted Stem Cells. N. Sathy, A.C. Daly, T. Gonzalez-Fernandez, G.M. Cunniffe, D.P. Olvera, N. Dunne, H.O. McCarthy, E. Alsberg, T.H. Donahue, D.J. Kelly. Acta Biomaterialia, 88 (2019) 314-324.

Pore-forming Bioinks to Enable Spatio-temporally Defined Non-viral Gene Delivery in Bioprinted Tissues. Gonzalez-Fernandez, S. Rathan, C. Hobbs, P. Pitacco, F.E. Freeman, G.M. Cunniffe, H.O. McCarthy, V. Nicolosi, N. Dunne, F.J. O’Brien, D.J. Kelly. Journal of Controlled Release, 301 (2019) 13-27. Featured on the Journal’s cover, editor choice.

Journal cover:

Defining Hydrogel Properties to Instruct Lineage- and Cell-Specific Mesenchymal Differentiation. P. Hung, J.N. Harvestine, A.M. Saiz, T. Gonzalez-Fernandez, D.E. Sahar, M.L. Weiss, J.K. Leach. Biomaterials, 189 (2019) 1-10.

2018

Controlled Non-viral Gene Delivery in Cartilage and Bone Repair: Current Strategies and Future Directions. Gonzalez-Fernandez, F.J. O’Brien, D.J. Kelly. Advanced Therapeutics,1 (2018) 1800038.

Dual Non-Viral Gene Delivery from Microparticles Within 3D High-density Stem Cell Constructs for Enhanced Bone Tissue Rngineering. McMillan, M. Khanh Nguyen, T. Gonzalez-Fernandez, P. Ge, X. Yu, W. Murphy, D.J. Kelly, E. Alsberg. Biomaterials, 161 (2018) 240-255.

2017

3D Bioprinting for Cartilage and Osteochondral Tissue Engineering.C. Daly, F.E. Freeman, T. Gonzalez-Fernandez, S.E. Critchley, J. Nulty, D.J. Kelly. Advanced Healthcare Materials, 6 (2017) 1700298.

RALA Complexed α-TCP Nanoparticle Delivery to Mesenchymal Stem Cells Induces Bone Formation in Tissue Engineered Constructs In Vitro and In Vivo.N. Sathy, D. Olvera, T. Gonzalez-Fernandez, G.M. Cunniffe, S. Pentlavalli, P. Chambers, O. Jeon, E. Alsberg, H.O. McCarthy, N. Dunne, T. L. Haut Donahue, D.J. Kelly. Journal of Materials Chemistry Part B, 5 (2017) 1753-1764.

Mesenchymal Stem Cell Fate Following Non-viral Gene Transfection Strongly Depends on the Choice of Delivery Vector. Gonzalez-Fernandez, B.N. Sathy, C. Hobbs, G.M. Cunniffe, H.O. McCarthy, N.J. Dunne, V. Nicolosi, F.J. O’Brien, D.J. Kelly. Acta Biomaterialia, 55 (2017) 226-238.

3D Bioprinting of PCL Reinforced Gene Activated Bioinks for Bone Tissue Engineering.M. Cunniffe*, T. Gonzalez-Fernandez*, A.C. Daly, B.N. Sathy, O. Jeon, E. Alsberg, D.J. Kelly. Tissue Engineering Part A, 23 (2017) 240-255. (*Authors contributed equally).

2016

Gene Delivery of TGF-β3 and BMP2 in an MSC-Laden Alginate Hydrogel for Articular Cartilage and Endochondral Bone Tissue Engineering. Gonzalez-Fernandez, E.G. Tierney, G.M. Cunniffe, F.J. O’Brien, D.J. Kelly. Tissue Engineering Part A, 22 (2016), 776-787.