by rap318 | Sep 20, 2022 | Research Project
There has been rising demand to isolate rare cells, such as circulating tumor cells (CTCs) at an ultralow concentration, which is critical in prognosis and early diagnosis of cancer. We designed a novel surface to significantly enhance rare cell capture efficacy....
by rap318 | Sep 20, 2022 | Research Project
Patient-derived organoids contain more heterogeneity and tissue architecture of the parental tumor than tumor cell lines, therefore providing the possibility for in vitro personalized prediction on the anticancer drug responses. Lung cancer remains one of the most...
by rap318 | Sep 20, 2022 | Research Project
Deterministic lateral displacement (DLD) is a robust passive method that uses continuous flow in a microfluidic device for small-scale particle separation, such as beads, droplets, leukocytes, cancer cells, viruses, bacteria, and DNA. The particles separate after...
by rap318 | Sep 20, 2022 | Research Project
Detection and characterization of rare tumor cells in patients’ blood is important for the diagnosis and monitoring of cancer. The traditional way via fluorescent images requires a series of tedious experimental procedures and often impacts the viability of...
by rap318 | Sep 20, 2022 | Research Project
Many deep-learning-based problems depend on a significant amount and high quality of the dataset, while in the “small data” regime, less work and related applications have been established. The computational cost of fluid dynamics simulations limits the scale,...
by rap318 | Sep 20, 2022 | Research Project
We report a microfluidic vessel-on-a-chip platform for recapitulating several key metastatic steps of tumor cells in blood vessels on the same chip, including intravasation, circulating tumor cell (CTC) vascular adhesion, and extravasation. Due to its excellent...
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