Deformations and Rupture of Lipid Vesicles in Fluid Flow

Another project that we are working on now is to understand the deformations and rupture of lipid vesicles in fluid flow. The pore formation and rupture of lipid vesicles cannot be captured by continuum scale models. Thus, we are working on coupling the coarse-grained...

Multiscale Modeling of Biological Membrane

Quantifying the characteristics of biological membranes is challenging. The multiscale nature of biological phenomena, complex structure, and non-equilibrium properties are some of the main difficulties. The focus of this project is to develop cellular and subcellular...

Data Analyzing in Microfluidic Experiments with Machine Learning

Modern machine learning algorithms are implemented to help to extract the information from microfluidic experiments and to simplify the fluid-structure interaction simulation with reduced cost. In detail, this research involves 1) a multiplex application of a machine...

Drug Delivery via Red Blood Cell Hitchhikers

Among all drug carriers, erythrocytes (known as red blood cells [RBC]) represent a potentially fascinating and, in some respects, unique carrier for drug delivery. Delivery of nanoparticle (NP)-based agents via their attachment on the RBC membrane is typically...

Intracellular Drug Delivery via Rapid Squeezing

Intracellular delivery of functional macromolecules is essential for biological research and medical application. For example, DNA and RNA delivery has been studied for gene therapy and CRISPR-based biosensing; enzymes and other proteins delivery has been investigated...