Chang, En Hyung (Tony)

En Hyung Chang

Areas of Research

Natural antibiotics
Bacterial toxins
Bacterial resistance
Biophysics

Publications and/or Posters

Chang, E.H., Huang, J., Lin, Z., Brown, A.C. Catechin-mediated restructuring of a bacterial toxin inhibits activity Biochimica et Biophysica Acta – General Subjects, Volume 1863, Issue 1, January 2019

Osickova, A., Balashova, N., Masin, J., Sulc, M., Roderova, J., Wald, T., Brown, A.C., Koufos, E., Chang, E.H., Giannakakis, A., Lally, E.T., Osicka, R. Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding Emerging Microbes and Infections, Volume 7, Issue 1, 1 December 2018

Krueger, E., Hayes, S., Chang, E.H., Yutuc, S., Brown, A.C. Receptor-Based Peptides for Inhibition of Leukotoxin Activity, ACS Infectious Diseases, Volume 4, Issue 7, 13 July 2018

Koufos, E., Chang, E.H., Rasti, E.S., Krueger, E., Brown, A.C. Use of a Cholesterol Recognition Amino Acid Consensus Peptide to Inhibit Binding of a Bacterial Toxin to Cholesterol, Biochemistry, Volume 55, Issue 34, 9 August 2016

Profile

En Hyung (Tony) Chang was born and grew up in Seoul, South Korea and moved to Canada when he was in high school. Upon Finishing high school, he joined chemical engineering program in Purdue University. He worked as an undergraduate researcher in Dr. Chongli Yuan’s lab and mainly worked with hydromethylation of DNA. Currently, he is a Doctoral student in Dr. Angela. C. Brown’s lab at Lehigh University. His research focuses on the antibacterial mechanism of natural antibiotics, catechin.