Biomechanics of Viral Entry and Vesicle Exocytosis (Synaptic Transmission)

We are interested in the biomechanics of how things get out of or into a cell.  We work on two specific problems:

  1. Molecular details of synaptic transmission, in which bundles of SNARE proteins cause docking and fusion of synaptic vesicles to the cytosolic side of the plasma membrane.

2. Viral entry into cells, specifically that of the Ebola virus